Buildings used for production of medicated feed shall provide adequate space for equipment, processing, and orderly receipt and storage of medicated feed. Areas shall include access for routine maintenance and cleaning of equipment. Buildings and grounds shall be constructed and maintained in a manner to minimize vermin and pest infestation.
21 CFR Part 225 · Current Good Manufacturing Practice for Medicated Feeds
§ 225.120 Buildings and grounds
Independent copy, not an official legal edition. 21 CFR is a U.S. Government work in the public domain; this text comes from the eCFR and the annual CFR edition, and may lag recent amendments. The authoritative version is on ecfr.gov. Compliome is not affiliated with or endorsed by FDA. Not legal advice.
What FDA inspectors cite under § 225.120
Form FDA 483 observations citing this section, fiscal years 2009–2024 (Veterinary Medicine).
- Vermin and pest infestation 60
- Buildings--space and access 3
Warning letters citing § 225.120
7 FDA warning letters since 2017 cite this section :
- J.D. Heiskell Holdings LLC 12 Jun 2025
- Furst-McNess Company 12 Mar 2024
- Appleton City Feed Service LLC 1 Nov 2023
- CHS Inc./CHS River Plains 30 Nov 2022
- Dairy Feeds, Inc. 27 Jul 2022
- Bartlett Cooperative Association Bartlett Feed Mill 20 Oct 2021
- Gilman Cooperative Creamery Association 5 Oct 2018
FDA guidance that cites § 225.120
- CVM GFI #272 Practices to Prevent Unsafe Contamination of Animal Feed from Drug Carryover 30 Jan 2023
- Draft Guidance for Industry: Questions and Answers on the Accredited Third-Party Certification Program draft 28 Apr 2022
- CVM GFI #72 GMP'S For Medicated Feed Manufacturers Not Required to Register and be Licensed with FDA 1 May 1998
Amendment history
Federal Register documents that created or amended this section.
- 41 FR 52618 30 Nov 1976